Education & Research

Anesthesia Research & Development — Hartford Division

IAA is affiliated with multiple research and development programs, allowing team members to work on cutting edge anesthesia research. Contact us to learn more. 



Hartford Division — Prospective Clinical Trials

Left Uterine Displacement Study- Maternal and Fetal Effects of Left Uterine Displacement during Cesarean Delivery: A Randomized Controlled Trial.

PI: Adam Sachs, MD /  IRB# HHC-2015-0284 

During Cesarean Delivery pregnant women are frequently tilted to the left 15 degrees to reduce compression of the major blood vessels by the uterus.  Despite this common practice, there is no conclusive evidence to support this practice.  In fact it may even be deleterious to have women positioned in this position.  The aim of the study is to determine whether or not tilting women to the left during cesarean section (CS) is helpful or detrimental. To investigate this question, women will be randomly assigned to either be tilted to the left during CS or positioned flat on the table.  Fetal acid base status, vasopressor/phenylephrine use, patient satisfaction, maternal complications, and fetal complications will all be collected and compared.

TAPLIP- Bilateral Mid-Abdominal Transverse Abdominis Plane (TAP) And Rectus Sheath (RS) Blocks comparing the use of LIPosomal Bupivacaine/Bupivacaine Admixture Vs. Regular Bupivacaine With Adjuncts In Laparoscopic Colectomy Procedures: A Single-Center, Triple Blinded, Randomized-Controlled Trial.

PI: Kevin Finkel, MD/ NCT # NCT05224089/ IRB # HHC-2021-0331

This study is a randomized control trial, in collaboration with the Colorectal surgery at Hartford Hospital. The primary outcomes include VAS pain scores, the amount of postop. opioid and non-opioid analgesics consumed, block duration, postoperative nausea and vomiting (PONV), hospital and PACU length-of-stay (LOS), the long-term effect of TAP and RS blocks intervention on the incidence of chronic pain, and patient’s overall satisfaction. The study is approved by HHC IRB and open to enrollment, also registered with the National Clinical Trials.

Acupuncture- Open-Label Randomized Controlled Trial to Assess Preoperative Acupuncture for Patients Undergoing Total Knee or Hip Arthroplasty.

PI: Pranjali Kainkaryam, MD/ IRB# HHC-2021-0348

This study is a randomized control trial, in collaboration with orthopedic surgery at Bone and Joint Institute. The primary objective is the reduction in preoperative anxiety and postoperative pain in high-anxiety patients undergoing THA or TKA while the secondary objectives include the safety of preoperative acupuncture, postoperative nausea and vomiting, postoperative opioid consumption, and patients’ satisfaction. The study is approved by HHC IRB and open to enrollment.

GATHER- General Anesthesia vs. Sedation for Transcatheter Aortic Valve Replacement a Randomized Controlled Prospective Study.

PI: Joseph Hinchey, MD, PhD / IRB# HHC-2021-0222

This study is a randomized control study, in collaboration with the Cardiac Surgery and Interventional Cardiology Departments at Hartford Hospital. The study is about comparing clinical outcomes between GA to conscious sedation for patients undergoing TAVR procedure. The primary outcomes include cost-related factors such as duration of TAVR procedure, PACU and hospital length-of-stay, time needed to recover from general anesthesia or sedation, the occurrence of intraoperative and postoperative compromised heart function or heart decompensation, ICU admission, or prolonged ICU admission, inotropes and/or vasopressors administered, and airway management, including the time needed to be extubated (ETT or LMA). The study is approved by HHC IRB and open to enrollment.

STORMING- A Pilot Study for Feasibility and Safety of Satellite Ganglion Block (SGB) to Control Paroxysmal Sympathetic Hyperactivity (PSH) After Severe Traumatic Brain Injury (TBI)

PI: Yasser Al-Baghdadi, MD / IRB# HHC-2022-0019

This is a pilot study in collaboration with the neuro-intensive care unit at Hartford Hospital ICU. The primary outcomes are to determine the safety and feasibility of Stellate Ganglion Block in patients with TBI associated with PSH attacks in the ICU and to determine if SGB can improve symptoms associated with PSH (hypertension, hyperthermia, tachycardia, tachypnea, diaphoresis, dystonia). This study is still under the revision of HHC IRB for final approval. It was approved by IAA for the financial support of the study intervention.

Contact Us

If you would like to learn more about IAA Hartford Division Research, please contact us. We would love to hear from you.

Mailing Address
Department of Anesthesia Research and Development / Department of Anesthesiology
Hartford Hospital, 80 Seymour Street, JB321, Hartford, CT 06102

Office Hours
Monday – Friday 8:00 am – 5:00 pm

Kevin J. Finkel, MD, FASA
Director of Research, Hartford Division
Anesthesia Research & Development Department, Hartford Division
Email Dr. Finkel

Aseel Walker, MD
Senior Project Management Specialist
Anesthesia Research & Development Department, Hartford Division
Email Aseel Walker

 

Med students, residents, fellows, and others are encouraged to contact:

Kevin J. Finkel, MD, FASA

Kevin J. Finkel, MD, FASA
Director of Clinical Research,
Hartford Division

Tel: (860) 972-2117
Fax: (860) 545-1784
Email Dr. Finkel

Aseel Walker, MD
Senior Project Management Specialist
Hartford Hospital
Email Aseel