IAA is affiliated with multiple research and development programs, allowing team members to work on cutting edge anesthesia research. Contact us to learn more.
Does The Use of Propofol Sedation For Ventilated Septic Patient In The ICU Influence Recovery From Infection And Mortality Rates?
(PI) Dhamodaran Palaniappan, MD / IRB #: E-HHC-2023-0008
A single-center, retrospective cohort study at Hartford Hospital ICU. The purpose of this study is to investigate the influence propofol has on outcomes for ICU patients with sepsis. The hypothesis is that ICU patients who received propofol for sedation will have worse infectious outcomes when compared to patients that did not receive propofol. Additional hypothesis is that there is a positive correlation between the total amount of propofol received by ICU patients and the presence of unwanted outcomes. This study is approved by HHC IRB and is in the data collection stage
LEADACT – Impact of the Affordable Care Act on Disparities in Lower Extremity Amputation and Post-Amputation Rehabilitation in the United States: Retrospective Review of the Vascular Quality Initiative, Vascular Study Group of New England, and Hartford Hospital Data Registries.
PI: Trevor Sutton, MD, MBA / IRB# HHC-2021-0321
This study is a collaboration with the Heart and Vascular Research Institute and Vascular Surgery Department at Hartford Hospital. The objective of this study is to compare the preoperative and postoperative management trajectories, surgical outcomes, and post-amputation rehabilitation outcomes of patients with lower extremity peripheral vascular disease during two time periods; prior to the Affordable Care Act (2004 – 2009) and following its implementation (2015- 2020). The study is approved by HHC IRB and is in the data collection stage.
Thoracic Trauma Study- A Retrospective Cohort Study to Compare Clinical Outcomes of Continuous Regional Plane Blocks (Erector Spinae or Serratus Anterior) vs. Thoracic Epidural Catheter vs. No Regional Block in Patients With Fractured Ribs Thoracic Trauma
PI: Kevin Finkel, MD/ Co-PI: Nishant Merchant, MD / IRB # HHC-2022-0052
This study is a retrospective review in collaboration with the Trauma Surgery and Emergency Trauma Departments at Hartford Hospital. The primary objective is to determine if there are differences in using either CESPB, CSAPB, or epidural catheters on the following clinical outcomes: opioid consumption, pain control, hospital and ICU length-of-stay, the incidence of procedural complications, to assess hemodynamic instability, the need for and the amount vasoactive support, management of VTE prophylactic medications, incidence of complications like delirium; pneumonia, UTI, and mortality rate. Other trauma-related outcomes include time to the first ambulation, time to discharge from ED, time to initiate regional anesthesia regimen, ventilator duration, rate of tracheostomy, de-saturation episodes. Secondary objectives include a comparison of all three regional analgesia types as one group to a non-block group in terms of pain control, opioid consumption, hospital, and ICU length-of-stay, and the incidence of complications. The tertiary objective is to assess whether there were socioeconomic, ethnic, or racial disparities present in the treatment of those patients. This study is currently approved by IRB and open.
PI: Carla Maffeo-Mitchell, MD / IRB #E-HHC-2021-0097
A single-center, retrospective cohort study at Hartford Hospital in the protocol stage looking at the evolution of serratus anterior and erector spinae blocks for video-assisted thoracoscopic surgical patients. The primary outcomes of this study include VAS pain scores, hospital length-of-stay, and opioid consumption. This study is approved by HHC IRB and is in the data collection stage.
If you would like to learn more about IAA Hartford Division Research, please contact us. We would love to hear from you.
Department of Anesthesia Research / Department of Anesthesiology
80 Seymour Street, JB321
Hartford, CT 06102
Monday – Friday 8:00 am – 5:00 pm